JEJEUNAL AMYLOIDOSIS AS OCCULT BLEED IN POST RENAL TRANSPLANT RECIPIENT

Dr. Dr Anju
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35 year old gentleman, diagnosed chronic kidney disease in 2010 ,received renal allograft in August 2014.His native kidney disease was IgA Nephropathy.In November 2019 he developed graft dysfunction and hemodialysis was initiated. He presented with Hb 5 g/dl. His stool occult blood was positive. CT Angiography showed jejunal loop thickening? ischemia/enteritis. Push enteroscopy revealed jejunal ulcerations with polypoidal protrusions. Jejunal biopsies showed amyloid deposition in the lamina propria with Congo red stain demonstrating apple green birefringence under polarized light.

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Gastrointestinal amyloidosis is a rare cause for gastrointestinal bleed. Accurate diagnosis requires knowledge of endoscopic appearance and histological findings.

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Tags: Gastroenterology