Easily set Dexmed infusion

Dr.Girijanandan D
Figure 1
Dexmedetomidine is an IV sedative that does not cause respiratory depression. The following is an easy way to titrate the right dose. The infusion rates for the loading dose at 1mcg/kg (in mls/hour) of a 4mcg/ml solution is always 1.5 times the body weight. Similarly the infusion rate for the maintenance dose could be easily begun at 0.4 mcg/kg/hour dosage by calculating the maintenance rate (in mls/hour) by the equation, 1/10th of the body weight. The drug could be titrated from this infusion rate for a particular setting extending from 0.2 to 0.7 mcg/kg/hour.

Message
Middle dose is a safe dose to start with.

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Tags: Critical Care